BPRC Publications

Publications for 2015

  • 't Hart B.A.
    Reverse translation of failed treatments can help improving the validity of preclinical animal models.
    2015 Eur. J. Pharmacol 759: 14-18.
  • 't Hart B.A., Bogers W.M., Haanstra K.G., Verreck F.A. and Kocken C.H.
    The translational value of non-human primates in preclinical research on infection and immunopathology.
    2015 Eur. J. Pharmacol 759: 69-83.
  • 't Hart B.A., van Kooyk Y., Geurts J.J. and B. Gran.
    The primate autoimmune encephalomyelitis model; a bridge between mouse and man.
    2015. Ann Clin Transl Neurol 2: 581-593.
  • 't Hart, B.A.
    Why does multiple sclerosis affect only human primates?
    2015. MS Journal in press. Jun 25. pii: 1352458515591862. [Epub ahead of print]
  • Arnold I.C., Hutchings C., Kondova I., Hey A., Powrie F., Beverley P., Tchilian E.
    Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis.
    Vaccine. 2015 Apr 8;33(15):1808-14
  • Bakker J., Ouwerling B., Heidt P.J., Kondova I., and Langermans J.A.M.
    Advantages and Risks of Husbandry and Housing Changes to Improve Animal Wellbeing in a breeding Colony of Common Marmosets (Callithrix jacchus).
    J. Am. Assoc. Lab. Anim. Sci. 2015;54(3):273-9
  • Bevaart L., Aalbers C.J., Vierboom M.P., Broekstra N., Kondova I., Breedveld E., Hauck B., Wright J.F., Tak P.P., Vervoordeldonk M.J.
    Safety, Biodistribution, and Efficacy of an AAV-5 Vector Encoding Human Interferon-Beta (ART-I02)
    Delivered via Intra-Articular Injection in Rhesus Monkeys with Collagen-Induced Arthritis. Hum. Gene Ther. Clin. Dev. 2015; 26: 103-12.
  • Boes A., Spiegel H., Edgue G., Kapelski S., Scheuermayer M., Fendel R., Remarque E.J., Altmann F, Maresch D, Reimann A, Pradel G, Schillberg S, Fischer R.
    Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits.
    Plant Biotechnol J. 2015 Feb;13(2):222-34. doi: 10.1111/pbi.12255. Epub 2014 Sep 18.
  • Bogers W.M.J.M., Oostermeijer H., Mooij P., Koopman G., Verschoor E.J., Davis D., Ulmer J.B., Brito L.A., Cu Y., Banerjee K., Otten G.R., Burke B., Dey A., Heeney J.L., Shen X., Tomaras G.D., Labranche C., Montefiori D.C., Liao L., Haynes B., Geall A.J. and Barnett S.W.
    Potent immune responses in rhesus macaques induced by non-viral delivery of a self-amplifying RNA vaccine expressing HIV-1 envelope with a cationic nanoemulsion.
    J. Infect. Dis. 2015, 211(6):947-55.
  • Burm S.M., Zuiderwijk-Sick E.A., ‘t Jong, A.E.J., van der Putten C., Veth J., Kondova I. and Bajramovic J.J.
    Inflammasome-induced IL-1β secretion in microglia is characterized by delayed kinetics and is only partially dependent on inflammatory caspases.
    J. Neurosc. 35(2), 678-87 (2015). (2015).
  • Chain B., Arnold J., Akthar S., Brandt M., Davis D., Noursadeghi M.,
    Thabo Lapp, Ji C., Sankuratri S, Zhang Y, Govada L, Saridakis E, and Chayen N. A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody.
    PLoS ONE 2015, 10(6): e0128381.
  • Cheung Y.B., Xu Y., Remarque E.J. and Milligan P.
    Statistical estimation of antibody concentration using multiple dilutions.
    J. Immunol Methods. 2015 Feb;417:115-23. doi: 10.1016/j.jim.2015.01.001. Epub 2015 Jan 10.
  • de Groot N.G., Blokhuis J.H., Otting N., Doxiadis G.G. and Bontrop R.E.
    Co-evolution of the class I and KIR gene families in rhesus macaques: ancestry and plasticity.
    Immunol. Rev. 2015 Sep;267(1):228-45. doi: 10.1111/imr.12313.
  • Divis P.C., Singh B., Anderios F., Hisam S., Matusop A., Kocken C.H., Assefa S.A., Duffy C.W. and Conway D.J.
    Admixture in Humans of Two Divergent Plasmodium knowlesi Populations Associated with Different Macaque Host Species.
    PLoS Pathog. 2015 May 28;11(5):e1004888. doi: 10.1371/journal.ppat.1004888. eCollection 2015 May.
  • Dufour V., Poulin N., Curé C., Sterck E.H.M.
    Chimpanzee drumming: a spontaneous performance with characteristics of
    human musical drumming. Sci Rep. 2015 Jun 17;5:11320.
  • Dunham J., Lee L.F., van Driel N., Laman J.D., Ni I., Zhai W., Tu G.H., Lin J.C., Bauer J., 't Hart B.A. and Kap Y.S.
    Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis.
    J. Neuroimmune Pharmacol. 2015. Aug 11. [Epub ahead of print]
  • Evers E., de Vries H., Spruijt B.M. and Sterck E.H.M.
    Emotional bookkeeping and high partner selectivity are necessary for the emergence of partner-specific reciprocal affiliation in an agent-based model of primate groups.
    PlosOne 2015 Mar 18;10(3):e0118921
  • Faber B.W.1, Abdul Kadir K.2, Rodriguez-Garcia R.1, Remarque E.J.1, Saul F.A.3, Vulliez-Le Normand B.3, Bentley G.A.3, Kocken C.H.1 and Singh B.2.
    Low levels of polymorphisms and no evidence for diversifying selection on the Plasmodium knowlesi Apical Membrane Antigen 1 gene.
    PLoS One. 2015 Apr 16;10(4):e0124400. doi: 10.1371/journal.pone.0124400. eCollection 2015.
  • Geels M.J.1, Thøgersen R.L.1, Guzman C.A.2, Ho M.M.3, Verreck F.4, Collin N.5 , Robertson J.S.3, McConkey S.J.6, Kaufmann S.H.7 and Leroy O.8.
    TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development.
    Vaccine. 2015 Oct 5;33(41):5481-7. doi: 10.1016/j.vaccine.2015.01.079. Epub 2015 Feb 8.
  • Geest L., Keehnen M., Klomp R., Bakker J., van der Schilt R., Langermans J.A.M.
    A simple solution to prevent the abdominal migration of temperature loggers, and to facilitate their smooth retrieval post-study in macaques.
    IAT Journal 2015; 141: 59-61
  • Golla S.S., Klein P.J., Bakker J., Schuit R.C., Christiaans J.A., van Geest L., Kooijman E.J., Oropeza-Seguias G.M., Langermans J.A.M., Leysen J.E., Boellaard R., Windhorst A.D., van Berckel B.N., Metaxas A.
    Preclinical evaluation of [18F]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors.
    Nucl. Med Biol. 2015 Feb;42(2):205-12
  • Greenwood E.J., Schmidt F., Kondova I., Niphuis H., Hodara V.L., Clissold L., McLay K., Guerra B., Redrobe S., Giavedoni L.D., Lanford R.E., Murthy K.K., Rouet F., Heeney J.L.
    Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections.
    PLoS Pathog. 2015 Sep 11;11(9):e1005146.
  • Haanstra K.G., Dijkman K., Bashir N. et al.
    Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis.
    J. Immunol. 2015; 194: 1454-66.
  • Jagessar S.A., Dijkman K., Dunham J., t Hart B.A. and Kap Y.S.
    Experimental Autoimmune Encephalomyelitis in Marmosets.
    Methods in molecular biology. Clifton, NJ. 2016; 1304: 171-86.
  • Jagessar S.A., Heijmans N., Blezer E.L., Bauer J., Weissert R. and 't Hart B.A.
    Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant.
    2015. J. Neuroinflammation 12: 169.
  • Jonker M., Wubben J.A., 't Hart B.A. and Haanstra K.G.
    Lymphoid-Like Structures with Distinct B Cell Areas in Kidney Allografts are not Predictive for Graft Rejection.
    A Non-human Primate Study. Inflammation. 2015 Dec; 38(6):2191-202. doi: 10.1007/s10753-015-0202-5.
  • Kap Y.S., van Driel N., Arends R., Rouwendal G., Verolin M., Blezer E., Lycke N., ‘t Hart, B.A.
    Immune modulation by a tolerogenic myelin oligodendrocyte glycoprotein (MOG)10-60 containing fusion protein in the marmoset experimental autoimmune encephalomyelitis model.
    2015. Clin. Exp. Immunol. 180, 28-39.
  • Lastrucci C., Bénard A., Balboa L., Pingris K., Souriant S., Poincloux R., A Saati T., Rasolofo V., González-Montaner P., Inwentarz S., Moraña E.J., Kondova I., Verreck F.A., Sasiain M.D., Neyrolles O., Maridonneau-Parini I., Lugo-Villarino G. and Cougoule C.
    Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16+ monocyte population via the IL-10/STAT3 axis.
    Cell Res. 2015 Dec;25(12):1333-51. doi: 10.1038/cr.2015.123. Epub 2015 Oct 20.
  • Luttmann R., Borchert S.O., Mueller C., Loegering K., Aupert F., Weyand S., Kober C., Faber B. and Cornelissen G.
    Sequential/parallel production of potential Malaria vaccines - A direct way from single batch to quasi-continuous integrated production.
    J. Biotechnol. 2015 Nov 10;213:83-96. doi: 10.1016/j.jbiotec.2015.02.022. Epub 2015 Feb 28.
  • Mooij P., Koopman G., Drijfhout J.W., Nieuwenhuis I.G., Beenhakker N., Koestler J., Bogers W.M., Wagner R., Esteban M., Pantaleo G., Heeney J.L., Jacobs B.L., Melief C.J.
    Synthetic long peptide booster immunization in rhesus macaques primed with replication competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1.
    J. Gen. Virol. 2015; 96(Pt 6):1478-83.
  • Mooij P., Koopman G., Mortier D., van Heteren M, Oostermeijer H, Fagrouch Z, de Laat R, Kobinger G, Li Y, Remarque E.J., Kondova I., Verschoor E.J. and Bogers W.M.
    Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets.
    PLoS One. 2015 May 6;10(5):e0126132. doi: 10.1371/journal.pone.0126132. eCollection 2015.
  • Nam K., Munch K., Hobolth A., Dutheil J.Y., Veeramah K.R., Woerner A.E., Hammer M.F.; Great Ape Genome Diversity Project, Mailund T., Schierup M.H., Prado-Martinez J., Sudmant P.H., Kidd J.M., Li H., Kelley J.L., Lorente-Galdos B., Veeramah K.R., Woerner A.E., O'Connor T.D., Santpere G., Cagan A., Theunert C., Casals F., Laayouni H., Munch K., Hobolth A., Halager A.E., Malig M., Hernandez-Rodriguez J., Hernando-Herraez I., Prüfer K., Pybus M., Johnstone L., Lachmann M., Alkan C., Twigg D.,
    Extreme selective sweeps independently targeted the X chromosomes of the great apes.
    Proc. Natl. Acad Sci U S A. 2015 May 19;112(20):6413-8.
  • Nater A., Greminger M.P., Arora N., van Schaik C.P., Goossens B., Singleton I., Verschoor E.J., Warren K.S. and Krützen M.
    Reconstructing the Demographic History of Orang-utans using Approximate Bayesian Computation.
    Molecular Ecology 2015, 24 (2); 310–327
  • Ouattara A., Barry A.E., Dutta S., Remarque E.J., Beeson J.G. and Plowe C.V.
    Designing malaria vaccines to circumvent antigen variability.
    Vaccine 2015, Volume 33, Issue 52, 22 December 2015, Pages 7506–7512
  • Overduin-de Vries A.M., Spruijt B.M., de Vries H., Sterck E.H.M.
    Tactical deception to hide sexual behaviour: macaques use distance, not visibility.
    Behav. Ecol. Sociobiol. 2015;69(8):1333-1342
  • Petit O., Dufour V., Herrenschmidt M., De Marco A., Sterck E.H.M. and Call J.
    Inferences about food location in three cercopithecine species: an insight into the socioecological cognition of primates.
    Anim. Cogn. 2015
  • Phillips M.A., Lotharius J., Marsh K., White J., Dayan A., White K.L., Njoroge J.W., El Mazouni F., Lao Y., Kokkonda S., Tomchick D.R., Deng X., Laird T., Bhatia S.N., March S., Ng C.L., Fidock D.A., Wittlin S., Lafuente-Monasterio M., Benito F.J., Alonso L.M., Martinez M.S., Jimenez-Diaz M.B., Bazaga S.F., Angulo-Barturen I., Haselden J.N., Louttit J., Cui Y., Sridhar A., Zeeman A.M., Kocken C.H., Sauerwein R., Dechering K., Avery V.M., Duffy S., Delves M., Sinden R., Ruecker A., Wickham K.S.,
    A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
    Sci Transl Med. 2015 Jul 15;7(296):296ra111. doi: 10.1126/scitranslmed.aaa6645.
  • Plas R.L., Degens H., Meijer J.P., de Wit G.M., Philippens I.H., Bobbert M.F. and Jaspers R.T.
    Muscle contractile properties as an explanation of the higher mean power output in marmosets than humans during jumping.
    The Journal of experimental biology. 2015; 218: 2166-73.
  • Rosas-Aguirre A., Speybroeck N., Llanos-Cuentas A., Rosanas-Urgell A., Carrasco-Escobar G., Rodriguez H, Gamboa D., Contreras-Mancilla J., Alava F., Soares I.S., Remarque E., Alessandro D.U., and Erhart A.
    Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey.
    PLoS One. 2015 Sep 10;10(9):e0137458. doi: 10.1371/journal.pone.0137458. eCollection 2015.
  • Ruiz-Orera J., Hernandez-Rodriguez J., Chiva C., Sabidó E., Kondova I., Bontrop R.E., Marqués-Bonet T. and Albà M.M.
    Origins of De Novo Genes in Human and Chimpanzee.
    PLoS Genet. 2015 Dec 31;11(12):e1005721. doi: 10.1371/journal.pgen.1005721. eCollection 2015 Dec.
  • Sterck E.H.M., Olesen C.U. and Massen J.J.M.
    No costly pro-sociality among related long-tailed macaques (Macaca fascicularis).
    Journal of Comparative Psychology 2015 Aug;129(3):275-82
  • van der Wiel M.K., Otting N., Zeijdel L.M., Doxiadis G.G. and Bontrop R.E.
    Novel DRA alleles extracted from seven macaque cohorts.
    Tissue Antigens. 2015 Feb;85(2):146-8. doi: 10.1111/tan.12510.  
  • Van Heusden M., Stinissen P., 't Hart B.A. and N. Hellings.
    Cytomegalovirus: a culprit or protector in multiple sclerosis?
    Trends Mol Med. 2015 21: 16-23.
  • van Luijn M.M., van Meurs M., Stoop M.P., Verbraak E., Wierenga-Wolf A.F., Melief M.J., Kreft K.L., ’t Hart B.A., Luider T.M., Laman J.D. and Hintzen R.Q.
    Elevated expression of cerebrospinal fluid markers chromogranin A and clusterin by astrocytes in multiple sclerosis white matter lesions.
    J. Neuropathol. Exp. Neurol. 2015, Dec 18. pii: nlv004. [Epub ahead of print]
  • van Roy M., Ververken C., Beirnaert E., Hoefman S., Kolkman J., Vierboom M.P., Breedveld E., 't Hart B.A., Poelmans S., Bontinck L., Hemeryck A., Jacobs S., Baumeister J. and Ulrichts H.
    The preclinical pharmacology of the high affinity anti-IL-6R Nanobody(R) ALX-0061 supports its clinical development in rheumatoid arthritis.
    2015. Arthritis Res. Ther 17: 135.
  • Verstrepen B.E., Boonstra A. and Koopman G.
    Immune mechanisms of vaccine induced protection against chronic HCV infection in chimpanzees.
    World J. Hepatol, 2015; 7(1): 53-69.
  • Viebig N.K., D'Alessio F., Draper S.J., Sim B.K., Mordmüller B., Bowyer P.W., Luty A.J., Jungbluth S., Chitnis C.E., Hill A.V., Kremsner P., Craig A.G., Kocken C.H., Leroy O.
    Workshop report: Malaria vaccine development in Europe-preparing for the future.
    Vaccine. 2015 Nov 17;33(46):6137-44. doi: 10.1016/j.vaccine.2015.09.074. Epub 2015 Oct 1.
  • Vierboom M.P., Breedveld E., Kap Y.S., Mary C., Poirrier N., 't Hart B.A. and Vanhove B.
    Blockade of CD28 with a novel selective antagonist abrogates induction of Collagen-induced Arthritis in the Rhesus Monkey.
    2015. Clin. Exp. Immunol. ov 5. doi: 10.1111/cei.12739. [Epub ahead of print]
  • Vulliez-Le Normand B., Faber B.W,. Saul F.A., van der Eijk M., Thomas A.W., Singh B., Kocken C.H. and Bentley G.A.
    Crystal structure of Plasmodium knowlesi apical membrane antigen 1 and its complex with an invasion-inhibitory monoclonal antibody.
    PLoS One. 2015 Apr 17;10(4):e0123567. doi: 10.1371/journal.pone.0123567. eCollection 2015.

Books, correspondence, not peer reviewed, etc.

  • Molenbergh F., Chiers K., Bakker J., Langerman J.A.M., Decostere A., Saunders J., Cornillie P. and Bosseler L.
    Bone pathology of New and Old World monkeys.
    Vlaams Diergeneeskundig Tijdschrift 2015; 84: p. 10-17