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In total there are 168 English news articles.
We are pleased to present the BPRC 2017 Annual Scientific Report
Genetic properties of dormant form of malaria parasites understood at last
Thirty years after the discovery that certain types of malaria create so-called 'dormant' parasites, we have finally obtained a greater insight into their genetic properties. This constitutes a major breakthrough in our search for new medications, which are badly needed in our fight against this serious disease.
An international research team (with material supported by BPRC) has discovered a new orangutan species on Sumatra. The highlands of this Indonesian island, harbour a great ape species that is described by the researchers * as the Tapanuli orangutan (Pongo tapanuliensis). With only an estimated 800 tapanuli alive this is the most endangered great ape species in the world.
On 18 October 2017 Jordon Dunham successfully defended his thesis entitled `Translational Multiple Sclerosis Research in Primates`.
Plasmodium cynomolgi (P. cynomolgi) is closely related to the people malaria parasite Plasmodium vivax. This parasite causes each year millions of serious illnesses in endemic areas.
The development of an efficacious HIV-1 vaccine remains a global priority to prevent new cases of HIV-1 infection. Of the six HIV-1 efficacy trials to date, only one has demonstrated partial efficacy, and the immune correlates analysis of this trial revealed a role for binding antibodies and antibody Fc mediated effector functions.
The MHC system plays a central role in the recognition of pathogens. Most genes of the MHC system in humans and monkeys are very variable and can especially in Old World apes, such as macaques, occur in different numbers. Therefore, when testing new therapies for diseases in experimental animals it is important to know the variability and numbers of MHC genes of these animals.
MHC class I molecules play a central role in the defense of viruses. The study of the DNA that encodes the MHC can teach us a lot about the effects of pathogens on our immune system.
There are indications that partner choice of people is unconsciously focused on ensuring a progeny that is well-armed against pathogens. The Major Histocompatibility Complex (MHC) is a component of the immunesystem which plays an important role in the recognition of pathogens.